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![]() ![]() As long as the room is not cleared, Isaac can re-attempt a Death's List by leaving and re-entering.Losing this item will not remove stat rewards.If a non-marked enemy is killed, the skull will disappear and no bonuses will be granted for that room.A Soul Heart, a pill, a Key, a Bomb, or a Nickel.If all enemies in the room are cleared in the order they are marked, Isaac gains one of the following rewards at random:. ![]() Killing the marked enemy will cause the skull to move to a different enemy.The marked enemy will have bigger shadow.Upon entering a room, a skull appears over an enemy's head. ![]()
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